3Q Digital Employee Reviews About "Long Hours"

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Geneticists use maps lớn describe the location of a particular ren on a chromosome. One type of map uses the cytogenetic location khổng lồ describe a gene’s position. The cytogenetic location is based on a distinctive pattern of bands created when chromosomes are stained with certain chemicals. Another type of maps uses the molecular location, which is a precise mô tả tìm kiếm of a gene"s position on a chromosome. The molecular location is based on the sequence of DNA building blocks (nucleotides) that make up the chromosome.

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Cytogenetic location

Geneticists use a standardized way of describing a gene"s cytogenetic location. In most cases, the location describes the position of a particular band on a stained chromosome:

17q12

It can also be written as a range of bands, if less is known about the exact location:

17q12-q21

The combination of numbers & letters provide a gene"s “address” on a chromosome. This address is made up of several parts:

The chromosome on which the ren can be found. The first number or letter used khổng lồ describe a gene"s location represents the chromosome. Chromosomes 1 through 22 (the autosomes) are designated by their chromosome number. The sex chromosomes are designated by X or Y.

Sometimes, the abbreviations “cen” or “ter” are also used to lớn describe a gene"s cytogenetic location. “Cen” indicates that the gene is very close to lớn the centromere. For example, 16pcen refers khổng lồ the short arm of chromosome 16 near the centromere. “Ter” stands for terminus, which indicates that the gene is very close to the kết thúc of the phường or q arm. For example, 14qter refers to lớn the tip of the long arm, or the very end, of chromosome 14.

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The CFTR gen is located on the long arm of chromosome 7 at position 7q31.2.

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Molecular location

The Human Genome Project, an international research effort completed in 2003, determined the sequence of nucleotides for each human chromosome. This sequence information allows researchers to provide a more specific address than the cytogenetic location for many genes. A gene’s molecular address pinpoints the location of that gen in terms of nucleotides. It describes the gene’s precise position on a chromosome and indicates the size of the gene. Knowing the molecular location also allows researchers lớn determine exactly how far a gene is from other genes on the same chromosome.

Different groups of researchers often present slightly different values for a gene’s molecular location. Researchers interpret the sequence of the human genome using a variety of methods, which can result in small differences in a gene’s molecular address.